We use our own and third-party cookies to improve our services, customize our web site, enhance User browsing experience, measure and obtain usage statistics. By clicking on "Accept" you ACCEPT ITS USE. You can also CONFIGURE OR REFUSE the installation of cookies by clicking on "Settings" or "Reject". For more information, read our Cookies Policy.
Phenotypic characterization of X-linked hypophosphatemia in pediatric Spanish population
May 03 2021
This study shows that growth retardation and rickets were the most prevalent clinical manifestations at diagnosis in a large series of Spanish pediatric patients with XLH confirmed by mutations in the PHEX gene. Traditional treatment with phosphate and vitamin D supplements did not improve height or corrected hypophosphatemia and was associated with a risk of hyperparathyroidism and nephrocalcinosis. The severity of the disease was similar in males and females.